Saturday, August 21, 2010

Niacinamide for the heart, skin and mind

Niacinamide can be referred to as Vitamin- B3 and is likely one of the group of nutritional vitamins under the heading of B-complex. Niacinamide is fashioned by combining niacin and an amide molecule. Each niacin and niacinamide have totally different chemical properties and hence totally different effects on the human body. Niacin has reported results in decreasing blood levels of cholesterol whereas niacinamide has numerous effects attributed to vitamin B3. Vitamin B3 has positive effects in enhancing the well being of the gastrointestinal tract, skin and the nervous system. It also helps in dilating blood vessels and prevents ringing sensation in the ears (additionally referred to as tinnitus). It prevents dizziness in sufferers who've this disorder. Vitamin B3 additionally prevents a condition called pellagra attributable to deficiency of niacinamide. In girls, vitamin B3 additionally helps stop premenstrual headache.

What's the mechanism of action of vitamin B3? Niacinamide acts by helping in the release of energy from foods. It also assists in the organic synthesis of DNA which is important in the formation of chromosomes, a vital part of the nucleus of the cells. Among the many different effects of vitamin B3 are its beneficial role in the therapy of psychological depression and the prevention of artery disease. It is also reported to assist in the treatment of schizophrenia, a harmful mental illness. It has shown clear effects in prevention and treatment of headaches, especially those brought on by migraine. Migraine is prompted by spasm of blood vessels within the head. By its vasodilatory effects, Vitamin B3 has some effect in relieving the condition. Niacinamide also helps lessen the consequences of toxins in diet and in the atmosphere. Some report it helps those affected by leprosy.

What are the consequences of deficiency of vitamin B3? Among the many well documented effects of deficiency of B3 are fatigue and muscle weakness. There is also an inclination for loss of appetite and lightheadedness. Other signs include inflamed red tongue and dry crusty skin. Changes in skin include formation of coarse texture and these effects are more pronounced in skin exposed to the sunlight. There are also complaints of nausea and vomiting in many of these patients. The symptom complex or disease ensuing from lasting or long term deficiency of vitamin B3 is named pellagra. This can be characterised by three Ds -diarrhea, dementia and dermatitis. The dermatitis is characterised by inflammation and cracking with dry scaling of the skin described above. The notable function of this skin disease is sensitivity to the sun. Among the mental transformations is a tendency toward aggression in patients of pellagra. Other psychological changes are confusion and insomnia or sleeplessness. Notably, one other necessary impact is on the heart leading to a illness known as dilated cardiomyopathy, a disease disturbing the heart muscles. In its ultimate stage thus pellagra can even be deadly if left untreated, given the big variety of results vitamin B3 has on the human body. Further disturbances caused by vitamin B3 deficiency are psycho motor and psycho sensory disturbances as a result of its results on the nervous system.

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